TRANSCompel(R): a database on composite regulatory elements in eukaryotic genes
نویسندگان
چکیده
منابع مشابه
COMPEL: a database on composite regulatory elements providing combinatorial transcriptional regulation
COMPEL is a database on composite regulatory elements, the basic structures of combinatorial regulation. Composite regulatory elements contain two closely situated binding sites for distinct transcription factors and represent minimal functional units providing combinatorial transcriptional regulation. Both specific factor-DNA and factor-factor interactions contribute to the function of composi...
متن کاملIdentifying regulatory elements in eukaryotic genomes.
Proper development and functioning of an organism depends on precise spatial and temporal expression of all its genes. These coordinated expression-patterns are maintained primarily through the process of transcriptional regulation. Transcriptional regulation is mediated by proteins binding to regulatory elements on the DNA in a combinatorial manner, where particular combinations of transcripti...
متن کاملQuerying a Database of Regulatory Elements
In this paper, we present a new approach that will facilitate the process of drawing meaningful conclusions that are likely to be useful to a biologist who may be interested in only a specific functional aspect of the organism (rather than the entire genome). This is achieved by constructing a comprehensive relational database and an intelligent, userfriendly query system. With the help of simp...
متن کاملCombined experimental and computational approaches to study the regulatory elements in eukaryotic genes
The recognition of transcription factor binding sites (TFBSs) is the first step on the way to deciphering the DNA regulatory code. There is a large variety of experimental approaches providing information on TFBS location in genomic sequences. Many computational approaches to TFBS recognition based on the experimental data obtained are available, each having its own advantages and shortcomings....
متن کاملXpro: database of eukaryotic protein-encoding genes
Xpro is a relational database that contains all the eukaryotic protein-encoding DNA sequences contained in GenBank with associated data required for the analysis of eukaryotic gene architecture. In addition to the information found in the GenBank records, which includes properties such as sequence, position, length and description about introns, exons and protein-coding regions, Xpro provides a...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2002
ISSN: 1362-4962
DOI: 10.1093/nar/30.1.332